New Research Areas in Clinical Microbiology

Volker Gurtler

doi:10.1055/s-0043-1772845

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13 (

04

); 443-444

doi:

10.1055/s-0043-1772845

New Research Areas in Clinical Microbiology

Volker Gurtler^1,

1RMIT University, School of Applied Sciences, Bundoora, Melbourne, Australia

Address for correspondence Volker Gurtler, BSc (Hons), MSc, PhD, RMIT University, School of Applied Sciences, Bundoora Campus, PO Box 71, Bundoora, 3083, Australia (e-mail: volker.gurtler@gmail.com)

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This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)

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This article was originally published by Thieme Medical and Scientific Publishers Pvt. Ltd. and was migrated to Scientific Scholar after the change of Publisher.

I would like to outline a few areas in Clinical Microbiology that have become major research disciplines over the last 10 years that may now impact Health and Allied Sciences. They encompass (1) COVID-19, (2) biofilms, (3) microbiomes, (4) nanotechnology, and (5) probiotics. As well as being direct research areas, they overlap with each other, and they are beginning to overlap in important ways with Health and Allied Sciences—hence the importance of contributing papers on these subjects to the Journal of Health and Allied Sciences NU (JHAS-NU).

There have been 43 publications on COVID-19 in JHAS-NU since the journal began in 2016, but the subject of all except for 6 of these articles is direct patient care. Three¹²³ have some diagnostic care component and the subject of the other three is the laboratory diagnosis of COVID-19.⁴⁵⁶ Since JHAS-NU began in 2016, there have been 2 publications on biofilms,⁷⁸ 3 publications on the microbiome,⁹¹⁰¹¹ 2 publications on nanotechnology,¹²¹³ and 1 publication on probiotics.¹⁴

The following are some examples of current research impacting Health and Allied Sciences in the above-mentioned areas:

A complete volume in Methods in Microbiology has been devoted to COVID-19 on diverse clinical subjects.¹⁵ This book includes chapters on the following:
- - Detection methods for of SARS-CoV-2 RNA (Chapter 1).
- - Chapter 2 describes a new method for analyzing the seasonal behavior of COVID-19 and Chapter 8 describes the application of this method in Australia by revealing a continental link to COVID-19 and seasonality.
- - The emerging variants of SARS-CoV-2 as revealed by current molecular diagnostics assays (Chapter 3).
- - Chapter 4 describes the therapy and diagnosis of COVID-19 using clustered regularly interspaced short palindromic repeats (CRISPR).
- - Nanotechnological strategies for COVID-19 vaccine development (Chapter 5).
- - The detection of immune responses to SARS-CoV-2 by hypersensitivity methods (Chapter 6).
- - How hesitancy to get vaccinated against COVID-19 might be overcome (Chapter 7).
- - Chapter 9 reviews the use of COVID-19 vaccines for high-risk and immunocompromised patients.
A recent methodological review describes technology that has the potential to be translated into clinics for better prevention, detection, and personalized treatment of biofilm-related infections.¹⁶ The book that this chapter is contained in also has many other chapters on Biofilms that are worth reading.
The Microbiome has been implicated in many different human anatomical sites including the gut–lung axis and its potential in improving or producing vaccines against COVID-19.¹⁷
Nanotechnology has now found its way into many areas of Health and Allied Sciences including new antimicrobial agents,¹⁸ treatment of osteoarthritis,¹⁹ cancer therapy,²⁰ wound healing,²¹ and many other applications.²²
Probiotics are bacteria that are ingested for positive health outcomes that are present in many foods such as yoghurt and sour dough bread. They are now also available in medicinal capsules for ingestion. Furthermore, a recent article has reviewed the potential of probiotics as ingestible antiviral agents to manage COVID-19.²³

Consequently, it is hoped that the readers and contributors to JHAS-NU are encouraged and inspired to contribute to one or more of the five above-mentioned areas of research.

Conflict of Interest

None declared.

References

Dsouza S T, Hegde N M, Pais P K. e-learning: an uphill to reshaping learning in dentistry in India in the COVID-19 pandemic era. J Health Allied Sci NU. 2021;12(02):175-178.
[Google Scholar]
Madiyal A, Bhat S, Babu S G, Achalli S. Impact of COVID-19 on dental education. J Health Allied Sci NU. 2021;11(02):057-60.
[Google Scholar]
Prasad K D, Prasad A D, Parakh K M. Coronavirus and its impact on dental fraternity. J Health Allied Sci NU. 2020;10(02):49-56.
[Google Scholar]
Karunasagar I, Karunasagar I. Ongoing COVID-19 global crisis and scientific challenges. J Health Allied Sci NU. 2020;10(01):01-2.
[Google Scholar]
Ramesh A, Potdar R, Bhandary R. Oral fluids—a diagnostic tool for COVID-19: a review. J Health Allied Sci NU. 2021;11(03):126-129.
[Google Scholar]
Srivatsa R, Hosmane B G, Venkataram R, Baikunje N. Pneumothorax in SARS-CoV-2 affected patients. J Health Allied Sci NU. 2021;12(01):79-82.
[Google Scholar]
D AP, Prasad R B, Shetty V, Shastry S C. Biofilms produced by Candida yeasts and its consequences: a review. J Health Sci NU. 2013;3(02):113-121.
[Google Scholar]
Rai A, Vittal V R, Mohan Raj R J. Isolation, characterization, and comparison of efficiencies of bacteriophages to reduce planktonic and biofilm-associated Staphylococcus aureus. J Health Allied Sci NU.. 2020;10(03):102-108.
[Google Scholar]
Ashwath P, Sannejal D A. The action of efflux pump genes in conferring drug resistance to Klebsiella species and their inhibition. J Health Allied Sci NU. 2021;12(01):24-31.
[Google Scholar]
Das D, Shenoy N, Shetty S. Understanding the risk of peri-implantitis. J Health Allied Sci NU 2023 (e-pub ahead of print).
[CrossRef] [Google Scholar]
Hegde N M, Mrinalini . Dysbiosis of oral microflora: a review. J Health Sci NU. 2018;8:34-39.
[Google Scholar]
Gananathan P, Chakraborty A, Karunasagar I. Cancer theranostics: bridging conventional and nano-photodynamic therapy. J Health Allied Sci NU. 2020;10(01):03-8.
[Google Scholar]
Kaira' S L, Singh R. Nanotechnology: the new era of technology. J Health Sci NU. 2012;2(04):88-92.
[Google Scholar]
K MJ, Shenoy N, Talwar A, Shetty S. Clinical effect of pro-biotic containing Bacillus coagulans on plaque induced gingivitis: a randomised clinical pilot study. J Health Allied Sci NU. 2017;7(03):7-12.
[Google Scholar]
Pavia S C, Gurtler V. Preface In: Pavia S C, Gurtler V, eds. Methods in Microbiology. Covid-19: Biomedical Perspectives. Vol. 50. Cambridge, MA: Elsevier; 2022. p. :xvii.
[Google Scholar]
Alcàcer-Almansa J, Arévalo-Jaimes V B, Blanco-Cabra N, Torrents E. Methods for studying biofilms: microfluidics and translation in the clinical context In: Gurtler V, Patrauchan M, eds. Methods in Microbiology. Vol. 53. Philadelphia, PA: Elsevier; 2023. p. :195-233.
[Google Scholar]
Oh S, Seo H. Dietary intervention with functional foods modulating gut microbiota for improving the efficacy of COVID-19 vaccines. Heliyon. 2023;9(05):e15668.
[Google Scholar]
Wahab S, Khan T, Adil M, Khan A. Mechanistic aspects of plant-based silver nanoparticles against multi-drug resistant bacteria. Heliyon. 2021;7(07):e07448.
[Google Scholar]
Wu C, He Y, Yao Y, Yang H, Lu F. Exosomes treating osteoarthritis: hope with challenge. Heliyon. 2023;9(01):e13152.
[Google Scholar]
Zhang W, Taheri-Ledari R, Ganjali F, et al.. Nanoscale bioconjugates: a review of the structural attributes of drug-loaded nanocarrier conjugates for selective cancer therapy. Heliyon. 2022;8(06):e09577.
[Google Scholar]
Nandhini N S, Sisubalan N, Vijayan A, et al.. Recent advances in green synthesized nanoparticles for bactericidal and wound healing applications. Heliyon. 2023;9(02):e13128.
[Google Scholar]
Ball S A, Patil S, Soni S. Introduction into nanotechnology and microbiology. Methods Microbiol. 2019;46:1-18.
[Google Scholar]
Tomkinson S, Triscott C, Schenk E, Foey A. The potential of probiotics as ingestible adjuvants and immune modulators for antiviral immunity and management of SARS-CoV-2 infection and COVID-19. Pathogens. 2023;12(07):928.
[Google Scholar]

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